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cd3 + cell fractions isolation  (STEMCELL Technologies Inc)

 
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    STEMCELL Technologies Inc cd3 + cell fractions isolation
    LOH 4q24 mapping and TET2 sequencing. (A) Topographical map illustrating overlapping regions of UPD4q24 (purple bars) and del4q24 (orange bars) in patients with myeloid malignancies. A minimally affected region on 4q24 (0.35 Mb), containing TET2 and PPA2, was identified in 18 of 398 patients studied (* indicates that some patients' DNA was not available for mutational screening; n = 3). (B) Representative examples of SNP-A karyograms (CNAG version 3.0) of chromosome 4 of both whole bone marrow cells and paired <t>CD3+</t> lymphocytes in 2 patients, demonstrating the somatic nature of acquired LOH4q24 and TET2 mutations, which are shown in corresponding ferrograms in the right portion of the figure. SNP-A karyograms: rows a and b correspond to the copy number as measured by the intensity of individual hybridization signals; row c represents frequency of heterozygous calls; and row d indicates the allelic imbalance with parental allele copy numbers.
    Cd3 + Cell Fractions Isolation, supplied by STEMCELL Technologies Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cd3 + cell fractions isolation/product/STEMCELL Technologies Inc
    Average 90 stars, based on 1 article reviews
    cd3 + cell fractions isolation - by Bioz Stars, 2026-03
    90/100 stars

    Images

    1) Product Images from "Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms"

    Article Title: Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms

    Journal: Blood

    doi: 10.1182/blood-2009-02-205690

    LOH 4q24 mapping and TET2 sequencing. (A) Topographical map illustrating overlapping regions of UPD4q24 (purple bars) and del4q24 (orange bars) in patients with myeloid malignancies. A minimally affected region on 4q24 (0.35 Mb), containing TET2 and PPA2, was identified in 18 of 398 patients studied (* indicates that some patients' DNA was not available for mutational screening; n = 3). (B) Representative examples of SNP-A karyograms (CNAG version 3.0) of chromosome 4 of both whole bone marrow cells and paired CD3+ lymphocytes in 2 patients, demonstrating the somatic nature of acquired LOH4q24 and TET2 mutations, which are shown in corresponding ferrograms in the right portion of the figure. SNP-A karyograms: rows a and b correspond to the copy number as measured by the intensity of individual hybridization signals; row c represents frequency of heterozygous calls; and row d indicates the allelic imbalance with parental allele copy numbers.
    Figure Legend Snippet: LOH 4q24 mapping and TET2 sequencing. (A) Topographical map illustrating overlapping regions of UPD4q24 (purple bars) and del4q24 (orange bars) in patients with myeloid malignancies. A minimally affected region on 4q24 (0.35 Mb), containing TET2 and PPA2, was identified in 18 of 398 patients studied (* indicates that some patients' DNA was not available for mutational screening; n = 3). (B) Representative examples of SNP-A karyograms (CNAG version 3.0) of chromosome 4 of both whole bone marrow cells and paired CD3+ lymphocytes in 2 patients, demonstrating the somatic nature of acquired LOH4q24 and TET2 mutations, which are shown in corresponding ferrograms in the right portion of the figure. SNP-A karyograms: rows a and b correspond to the copy number as measured by the intensity of individual hybridization signals; row c represents frequency of heterozygous calls; and row d indicates the allelic imbalance with parental allele copy numbers.

    Techniques Used: Sequencing, Hybridization



    Similar Products

    cd3 + cell fractions isolation  (STEMCELL Technologies Inc)
    90
    STEMCELL Technologies Inc cd3 + cell fractions isolation
    LOH 4q24 mapping and TET2 sequencing. (A) Topographical map illustrating overlapping regions of UPD4q24 (purple bars) and del4q24 (orange bars) in patients with myeloid malignancies. A minimally affected region on 4q24 (0.35 Mb), containing TET2 and PPA2, was identified in 18 of 398 patients studied (* indicates that some patients' DNA was not available for mutational screening; n = 3). (B) Representative examples of SNP-A karyograms (CNAG version 3.0) of chromosome 4 of both whole bone marrow cells and paired <t>CD3+</t> lymphocytes in 2 patients, demonstrating the somatic nature of acquired LOH4q24 and TET2 mutations, which are shown in corresponding ferrograms in the right portion of the figure. SNP-A karyograms: rows a and b correspond to the copy number as measured by the intensity of individual hybridization signals; row c represents frequency of heterozygous calls; and row d indicates the allelic imbalance with parental allele copy numbers.
    Cd3 + Cell Fractions Isolation, supplied by STEMCELL Technologies Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cd3 + cell fractions isolation/product/STEMCELL Technologies Inc
    Average 90 stars, based on 1 article reviews
    cd3 + cell fractions isolation - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    LOH 4q24 mapping and TET2 sequencing. (A) Topographical map illustrating overlapping regions of UPD4q24 (purple bars) and del4q24 (orange bars) in patients with myeloid malignancies. A minimally affected region on 4q24 (0.35 Mb), containing TET2 and PPA2, was identified in 18 of 398 patients studied (* indicates that some patients' DNA was not available for mutational screening; n = 3). (B) Representative examples of SNP-A karyograms (CNAG version 3.0) of chromosome 4 of both whole bone marrow cells and paired CD3+ lymphocytes in 2 patients, demonstrating the somatic nature of acquired LOH4q24 and TET2 mutations, which are shown in corresponding ferrograms in the right portion of the figure. SNP-A karyograms: rows a and b correspond to the copy number as measured by the intensity of individual hybridization signals; row c represents frequency of heterozygous calls; and row d indicates the allelic imbalance with parental allele copy numbers.

    Journal: Blood

    Article Title: Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms

    doi: 10.1182/blood-2009-02-205690

    Figure Lengend Snippet: LOH 4q24 mapping and TET2 sequencing. (A) Topographical map illustrating overlapping regions of UPD4q24 (purple bars) and del4q24 (orange bars) in patients with myeloid malignancies. A minimally affected region on 4q24 (0.35 Mb), containing TET2 and PPA2, was identified in 18 of 398 patients studied (* indicates that some patients' DNA was not available for mutational screening; n = 3). (B) Representative examples of SNP-A karyograms (CNAG version 3.0) of chromosome 4 of both whole bone marrow cells and paired CD3+ lymphocytes in 2 patients, demonstrating the somatic nature of acquired LOH4q24 and TET2 mutations, which are shown in corresponding ferrograms in the right portion of the figure. SNP-A karyograms: rows a and b correspond to the copy number as measured by the intensity of individual hybridization signals; row c represents frequency of heterozygous calls; and row d indicates the allelic imbalance with parental allele copy numbers.

    Article Snippet: Baseline patient characteristics SNP-A analysis DNA was extracted from patient marrow specimens and, when sample material allowed, CD3 + cell fractions were isolated using RoboSep (StemCell Technologies, Vancouver, BC).

    Techniques: Sequencing, Hybridization